The regular consumption of small quantities of alcohol — two drinks per day for men and one drink per day for women — appears to be associated with lower rates of cardiovascular events in most studies. These studies, however, do not have sound methodology. In most of these epidemiologic studies actual mortality rates are not stated and mainly relative risks are described.
Study question: Let’s examine the relationship between alcohol intake and risk of coronary heart disease (CHD) among men with type 2 diabetes. Because type 2 diabetes is associated with an increased risk of CHD, Tanasescu et al. studied the effect of alcohol on the risk of CHD.
Methods: This included the study of 2419 men who reported a diagnosis of diabetes at age 30 or older in the health professional’s follow-up study. Fifty new cases of CHD (81 nonfatal myocardial infarction and 69 fatal) were documented during 11,411 person-years of follow up.
Results: A questionnaire showed that alcohol use was inversely associated with risk of CHD. After controlling for body mass index (BMI), smoking, hypercholesterole-mia, physical activity level, and other variables, relative risk (RR) was 0.78, 0.6, and 0.48 ( p for trend ¼ 0.03) corres¬ponding to intake of less than 0.5 drinks per day, 0.5–2 drinks per day, and greater than 2 drinks per day.

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