Death may occur in young individuals who have no structural heart disease. The risk for pulmonary edema is related to the rapidity of ascent, the level of exertion, and individual susceptibility. The pulmonary symptoms may be accompanied by severe cerebral symptoms such as altered consciousness, ataxia, and brain herniation that progresses to coma and death. Thus individuals with symptoms of acute mountain sickness (headache, anorexia, vomiting, dizziness, and fatigue) and high altitude pulmonary edema may progress rapidly to severe cerebral symptoms and death.

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