Angiotensin-Converting Enzyme Inhibitors/ Angiotensin Receptor Blockers

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  • I. ACE INHIBITORS
    Since their introduction in 1980, angiotensin-converting enzyme (ACE) inhibitors, because of their unique pharmacologic properties, have proven superior to other vasodilators in the management of heart failure and have come to play a key role in the therapy of hypertension. They are particularly useful in hypertensive patients with diabetes and proteinuria.
  • II. ANGIOTENSIN II RECEPTOR BLOCKERS
    Angiotensin II receptor blockers (ARBs) have beneficial effects similar to those of ACE inhibitors, but angioedema occurs less, and cough rarely occurs compared to ACE inhibitors.
  • BIBLIOGRAPHY
    Bourassa, M. G. et al. Angiotensin II inhibition and prevention of atrial fibrillation and stroke. J. Am. Coll. Cardiol., 45:720–721, 2005.