V. DRUGS FOR CARDIAC ARREST A. Epinephrine (Adrenaline)
Magnesium sulfate is reported to expedite ventricular defibrillation and is indicated for polymorphic ventricular tachycardia, torsades de pointes, and management of hypomagnesemia. A dose of 1–2 mg IV is recommended.
H. Bretylium
Bretylium has been dropped from the VF/pulseless VT algorithm. This drug was used in the 1980s and 1990s for recurrent VF, but was only partially successful and never proven. In the late 1990s, severe problems with obtaining the raw materials curtailed manufacture. The world sources of bretylium appear to be nearly exhausted. Bretylium has a high incidence of side effects including hypotension. It has been replaced by amiodarone and beta-blocking agents.