Knudtson, M. L.,Wyse, K. G., Galbraith, P. D. et al. Chelation therapy for ischemic heart disease. A randomized controlled trial. JAMA, 287:481–6, 2002.
Merrill, L. K.,Wyse, G., Galbraith, P. D., Brant, R., Hildebrand, K., Paterson, D., Richardson, D., Burkart, C., and Burgess, E. for the
Program to Assess Alternative Treatment Strategies to Achieve Cardiac Health (PATCH) Investigators. JAMA, 287:481–486, 2002.
ABSTRACT
Context Chelation therapy using EDTA is an unproven but widely used alternative therapy for ischemic heart disease.
Objective To determine if current EDTA protocols have a favorable impact on exercise ischemia threshold and quality of life measures in patients with stable ischemic heart disease.