II. PATHOGENESIS OF DEEP VEIN THROMBOSIS
2. Inherited Diseases
Diseases that cause hypercoagulability states include:
• Factor V Leiden (a mutation in coagulation factor V that results in resistance to activated protein C or aPC)
• Antithrombin 3 deficiency
• Protein C deficiency
• Protein S deficiency
• Antiphospholipid antibody syndrome (see the chapter Antiphospholipid Antibody Syndrome)