II. CLINICAL FEATURES AND COMPLICATION OF TYPE 2 DIABETES
According to criteria developed by the National Diabetes Data Group, the presence of any of the classic symptoms such as polyuria and polydipsia, ketonuria, and rapid weight loss, together with a random venous plasma glucose level greater than 200 mg/dl (11.1 mmol/L) are considered diagnostic of diabetes.
IGT is also considered diagnostic of diabetes. Individ¬uals with a high IGT have plasma glucose levels higher than normal but lower than those considered diagnostic for diabetes mellitus. Of all patients with high IGT, 1–5% a year develop overt diabetes mellitus. Individuals with IGT have a greater than normal risk for macrovascular complications, but do not appear to have an increased risk for the more benign microvascular complications of diabetes.
C. Features
The characteristic features of type 1 and type 2 diabetes are given in Table 2. Complications of diabetes are illustrated in Fig. 3. The discussion of type 1 diabetes will follow the discussion below of type 2 diabetes.
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