The rapid reopening of an occluded coronary artery by administration of thrombolytic therapy within three hours of onset of chest pain or reopening the artery mechanically with PCI (balloon angioplasty and intracoronary stent) both provide beneficial improvements in mortality and morbidity in short- and long-term follow up. Several studies indicate that PCI may confer an improvement in outcomes compared with thrombolytic therapy in patients who present between 3 and 12 h after symptom onset. PCI with deployment of intracoronary stent has emerged as the treatment of choice for patients with ST segment elevation MI. Thrombolytic agents are used when facilities for PCI are not available or in selected patients.

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