Symptoms are caused by lack of blood supply to organs and fatigue, night sweats, and fever may occur. Involvement of the aortic root may cause severe aortic regurgitation, angina, and congestive heart failure. The sedimentation rate is assessed, but it may be normal in up to 50% of individuals with progressive lesions.
B. Management
Corticosteroid therapy, such as prednisone 1 mg/kg daily produces beneficial results in up to 60% of patients. Prednisone combined with cyclophosphamide or metho-trexate produces up to 40% remission, but relapse is common. Stenotic lesions throughout the vascular arterial system should be identified and corrected surgically if possible.

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